Zebrahub: Mapping Vertebrate Development One Cell at a Time
How does a single fertilized egg become a complex organism with hundreds of distinct cell types? This question has driven developmental biology for over a century, but we’ve lacked the resolution to truly see the process unfold. Zebrahub changes that. The Challenge Zebrafish are a workhorse model organism—transparent embryos, rapid development, genetic tractability. But previous atlases captured snapshots: this cell type exists at this stage. What we wanted was a movie: how do cell states transition over time? Where are the decision points? ...